Clinical pharmacist’s role in identification and management of medication errors in different wards of a hospital in Karachi

  • Anum Sattar Department of Pharmacy Practice, Faculty of Pharmacy, Ziauddin University, Karachi, Pakistan
  • Hina Rehman Department of Pharmacy Practice, Institute of Pharmaceutical Sciences, Jinnah Sindh Medical University, Karachi, Pakistan
  • Safila Naveed Department of Pharmaceutical Chemistry, Karachi University, Karachi, Pakistan
Keywords: Medication error, category of a medication error, clinical pharmacists, intervention

Abstract

Introduction: Medication errors are a frequent issue within healthcare facilities. The ratio of patients who suffer harm due to these errors, in contrast to those who do not, is a concerning 100:1. The research aimed to ascertain the prevalence and categories of medication errors, as well as the function of pharmacists in identifying and addressing these errors across different wards of a private tertiary care facility located in Karachi, Pakistan.

Methodology: A cross-sectional case study, conducted in a private hospital in Karachi and including 200 patients, was assumed to explore drug therapy errors and evaluate the pharmacist's contribution to their detection.

Results: Through the meticulous efforts of clinical pharmacists, an extensive assessment encompassing 200 patients was conducted with a gender distribution of 110 females (55%) and 90 males (45%). Within this cohort, a cumulative total of 250 errors (averaging 1.25 per patient) were detected and appropriately addressed. The observed frequencies of error categories were as follows:  above therapeutic dose (2.8%), sub-therapeutic dose (3.2%), dose adjustment (30%), drug-drug/drug-food interaction (3.6%), duplication of drug class (4.0%), dose Rounded off   (3.6%), intravenous to per oral switch (3.2%), incomplete drug order (4.8%), transcribing error (4.8%), wrong medication (22%), wrong frequency (8%), wrong route (3.6%), wrong dilution/incompatibility (3.6%), wrong infusion rate (1.6%), and miscellaneous (1.2%).

Conclusion This research highlighted the pervasive problem of medication errors and highlighted the critical role clinical pharmacists played in identifying and correcting errors to improve patient safety and streamline healthcare procedures.

Downloads

Download data is not yet available.

Author Biographies

Anum Sattar, Department of Pharmacy Practice, Faculty of Pharmacy, Ziauddin University, Karachi, Pakistan

Lecturer

Hina Rehman, Department of Pharmacy Practice, Institute of Pharmaceutical Sciences, Jinnah Sindh Medical University, Karachi, Pakistan

Assistnat Professor

Safila Naveed, Department of Pharmaceutical Chemistry, Karachi University, Karachi, Pakistan

Professor

References

Elliott RA, Camacho E, Jankovic D, Sculpher MJ, Faria R. Economic analysis of the prevalence and clinical and economic burden of medication error in England. BMJ Qual Saf. 2021; 30(2):96-105

DOI: https://doi.org/10.1136/bmjqs-2019-010206

Baraki Z, Abay M, Tsegay L, Gerensea H, Kebede A, Teklay H. Medication administration error and contributing factors among pediatric inpatient in public hospitals of Tigray, northern Ethiopia. BMC Pediatr. 2018; 18(1);1-8

DOI: https://doi.org/10.1186/s12887-018-1294-5

O’Brien F, Clapham D, Krysiak K, Batchelor H, Field P, Caivano G, et al. Making medicines baby size: The challenges in bridging the formulation gap in neonatal medicine. Int J Mol Sci. 2019; 20(11):2688

DOI: https://doi.org/10.3390/ijms20112688

Khayam MU. Medication errors assessment and prevention by a clinical pharmacist in pediatric wards of RMI Hospital Peshawar, KPK-Pakistan. Ann Pak Inst Med Sci. 2015;11(3):124-9.

Feinstein MM, Pannunzio AE, Castro P. Frequency of medication error in pediatric anesthesia: A systematic review and meta-analytic estimate. Paediatr Anaesth. 2018; 28(12):1071-7.

DOI: https://doi.org/10.1111/pan.13521

Estock JL, Murray AW, Mizah MT, Mangione MP, Goode JS, Eibling DE. Label Design Affects Medication Safety in an Operating Room Crisis: A Controlled Simulation Study. J Patient Saf. 2018; 14(2):101-6

DOI: https://doi.org/10.1097/PTS.0000000000000176

Nwasor EO, Sule ST, Mshelia DB. Audit of medication errors by anesthetists in North Western Nigeria. Niger J Clin Pract. 2014; 17(2):226-31

DOI: https://doi.org/10.4103/1119-3077.127563

Shah K, Lo C, Babich M, Tsao NW, Bansback NJ. Bar code medication administration technology: A systematic review of impact on patient safety when used with computerized prescriber order entry and automated dispensing devices. Can J Hosp Pharm. 2016;69(5):394

DOI: https://doi.org/10.4212/cjhp.v69i5.1594

Dean B, Barber N, Schachter M. What is a prescribing error? Quality in Health Care. 2000; 9(4):232-7

DOI: https://doi.org/10.1136/qhc.9.4.232

Kim Y, Schepers G. Pharmacist Intervention Documentation in US Health Care Systems. Hosp Pharm. 2003; 38(12):1141-7

DOI: https://doi.org/10.1177/001857870303801211

Smith F. Private local pharmacies in low- and middle-income countries: A review of interventions to enhance their role in public health. Trop Med Int Health. 2009; 14(3):362-72

DOI: https://doi.org/10.1111/j.1365-3156.2009.02232.x

Majumdar SR, Soumerai SB. Why most interventions to improve physician prescribing do not seem to work. Can Med Assoc J. 2003; 169(1):30-1

Хабриев РУ, Абашидзе АХ, Маличенко ВС. Роль развития системы регулирования обращения лекарственных средств в реализации права человека на наивысший достижимый уровень здоровья. Журнал зарубежного законодательства и сравнительного правоведения. 2016.2(57)):16-22.

Inch J, Watson MC, Anakwe-Umeh S. Patient versus healthcare professional spontaneous adverse drug reaction reporting: A systematic review. Drug Saf. 2012; 35(10):807-18.

DOI: https://doi.org/10.2165/11631650-000000000-00000

Gandhi TK, Weingart SN, Borus J, Seger AC, Peterson J, Burdick E, et al. Adverse drug events in ambulatory care. N Engl J Med. 2003 Apr 17;348(16):1556-64.

DOI: https://doi.org/10.1056/nejmsa020703

Avery AA, Barber N, Ghaleb M, Dean Franklin B, Armstrong S, Crowe S, et al. Investigating the Prevalence and Causes of Prescribing Errors in General Practice Prac Study; 2012.

Claesson CB, Burman K, Nilsson JL, Vinge E. Prescription errors detected by Swedish pharmacists. Int J Pharm Pract. 1995; 3(3):151-6.

DOI: https://doi.org/10.1111/j.2042-7174.1995.tb00809.x

Khoja T, Neyaz Y, Qureshi NA, Magzoub MA, Haycox A, et al. Medication errors in primary care in Riyadh city, Saudi Arabia. East Mediterr Health J. 2011; 17(2):156-59

DOI: https://doi.org/10.26719/2011.17.2.156

Zavaleta-Bustos M, Castro-Pastrana LI, Reyes-Hernández I, López-Luna MA, Bermúdez-Camps IB. Prescription errors in a primary care university unit: Urgency of pharmaceutical care in Mexico. Revista Brasileira de Ciências Farmacêuticas. 2008;44(1):115-25

DOI: https://doi.org/10.1590/S1516-93322008000100013

Garfield S, Barber N, Walley P, Willson A, Eliasson L. Quality of medication use in primary care - Mapping the problem, working to a solution: A systematic review of the literature. BMC Med. 2009; 7:1-8

DOI: https://doi.org/10.1186/1741-7015-7-50

Penm J, Moles R, Wang H, Li Y, Chaar B. Factors affecting the implementation of clinical pharmacy services in china. Qual Health Res. 2014; 24(3).

DOI: https://doi.org/10.1177/1049732314523680

Khan TM. Challenges to pharmacy and pharmacy practice in Pakistan. Australas Med J. 2011; 4(4):230.

DOI: https://doi.org/10.4066/AMJ.2011.488

Abubakar AR, Chedi BA, Simbak NB, Haque M. Medication error: The role of health care professionals, sources of error and prevention strategies. J Chem Pharm Res. 2014; 6(10):646-51.

Keers RN, Williams SD, Cooke J, Ashcroft DM. Prevalence and nature of medication administration errors in health care settings: a systematic review of direct observational evidence. Ann Pharmacother. 2013; 47(2):237-56.

DOI: https://doi.org/10.1345/aph.1R147

Cheragi MA, Manoocheri H, Mohammadnejad E, Ehsani SR. Types and causes of medication errors from nurse’s viewpoint. Iran J Nurs Midwifery Res. 2013; 18(3):228-31.

Anderson S. The state of the world’s pharmacy: A portrait of the pharmacy profession. J Interprof Care. 2002; 16(4):391-404

DOI: https://doi.org/10.1080/1356182021000008337

Azhar S, Hassali MA, Ibrahim MIM, Ahmad M, Masood I, Shafie AA. The role of pharmacists in developing countries: The current scenario in Pakistan. Hum Resour Health. 2009; 7:1-6

DOI: https://doi.org/10.1186/1478-4491-7-54

Struck P, Pedersen KH, Moodley P, Rasmussen M. A pilot study of pharmacist-initiated interventions in drug therapy in an Australian pediatric hospital. EJHP Sci. 2007; 13(4):105-2.

Altavela JL, Jones MK, Ritter M. A prospective trial of a clinical pharmacy intervention in a primary care practice in a capitated payment system. J Manag Care Spec Pharm. 2008; 14(9): 831-43

DOI: https://doi.org/10.18553/jmcp.2008.14.9.831

Bond CA, Raehl CL, Pitterle ME, Franke T. Health care professional staffing, hospital characteristics, and hospital mortality rates. Pharmacotherapy. 1999; 19(2):130-8.

DOI: https://doi.org/10.1592/phco.19.3.130.30915

Kaboli PJ, Hoth AB, McClimon BJ, Schnipper JL. Clinical pharmacists and inpatient medical care: A systematic review. Arch Intern Med. 2006;166(9):955-64

DOI: https://doi.org/10.1001/archinte.166.9.955

Published
2024-08-02
How to Cite
1.
Sattar A, Rehman H, Naveed S. Clinical pharmacist’s role in identification and management of medication errors in different wards of a hospital in Karachi. JSTMU [Internet]. 2Aug.2024 [cited 8Nov.2024];7(1):20-6. Available from: https://j.stmu.edu.pk/ojs/index.php/jstmu/article/view/278