Impact of the human genome assignment on biology and generation.
The Human Genome Project has revolutionized biology by deciphering a reference human genome sequence along with many other organisms’ complete sequences. The project reflects a great example of integrated inter-disciplinary approach to develop sophisticated technology and brought engineers, computer scientists and mathematicians at one platform with biologists. Further improvements have made from projects ENCODE, to find functional elements of genome; and Human Proteome Project, to map human proteins through the genetic map. Moving one step ahead, the gaps that were present to study evolution of many species are now decreasing due to better understanding of the genome. There has been an open approach to data sharing and open-source software, thereby data is publicly accessible for more breakthroughs from data banks such as GenBank. Physicians approach to practice medicine is changing and becoming more personalized as a result of this project. There has been development in treatments of many diseases for example through genome-wide association studies. Diseases prognosis and risk can be now more accurately predicted through the advancements in HGP. However, we are still in initial stages and in the process of understanding the huge data generated by HGP and its implications. Moreover, the ethical, social and political issues that arise due to this genetic research needs to be addressed alongside.
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