Flora of Pakistan: An ethnopharmacological perspective
Ethnopharmacology relies on the knowledge and use of traditional medicinal plants in various human diseases. These plants are a source of nutritional, medicinal and financial support to a greater part of Pakistani population, both in rural and urban setting. Either in the crude form or prepared pharmaceutical formulations, these plants are considered an essential part of the health-care and support system. Being regulated mainly as a part of the Complementary and Alternate Medicine, the plants and their products are used for the treatment of ailments of different organ systems. Their applications vary from being used as tonics, protectants and aids to being used as cytotoxic and antibacterial agents. Pakistan has a variety of biogeographical components which serves as a rich source of medicinal plants. With a deep-rooted history of Unani and Ayurvedic systems in Pakistan, the empirical knowledge about these plants has passed from one generation to the next. Some of these have also been recorded in the historical books of medicine and the components derived from them, now form an essential part of the modern-day pharmaceutical industry. This review provides the information of the flora of medicinal importance acquired from the various parts of Pakistan. The detailed information will help the researchers to develop an understanding about the biological activity and efficacy of phytochemical present in these plants.
Khan S. Climate classification of Pakistan. Int J Eco and Environ Geol. 2019; 10(2):60-71.
Khan DA, Ali Z, Iftikhar S, Amraiz D, Sadaf Zaidi NUS, Gul A, et al. Role of phytohormones in enhancing antioxidant defense in plants exposed to metal/metalloid toxicity. Plants Under Metal and Metalloid Stress: Responses, Tolerance and Remediation, 1st Ed. Singapore: Springer; 2018,367-400.
Iftikhar S, Ali Z, Khan DA, Zaidi NUS, Gul A, Babar MM. Arsenic toxicity: A south asian perspective. Mechanisms of Arsenic Toxicity and Tolerance in Plants, 1st Ed. Singapore: Springer; 2018,483-502.
Babar MM, Tariq A. Status of arsenic toxicity in the world. Mechanisms of Arsenic Toxicity and Tolerance in Plants, 1st Ed. Singapore: Springer; 2018, 457-81.
Turker H, Turkay M. Effects of Equisetum arvense plant extracts on the kidney stones and its diuretic action. Cell Mol Biol. 2016; 1(1):1-8.
Kala CP. Medicinal plants of the high altitude cold desert in India: Diversity, distribution and traditional uses. Int J Biodivers Sci Manag. 2006; 2(1):43-56.
Hussein S, Dhabe A. Ethnobotanical study of folk medicinal plants used by villagers in Hajjah district, Republic of Yemen. J. Med. Plants Stud.2018; 6(5):24-30.
Khan SW, Khatoon SU. Ethnobotanical studies on some useful herbs of Haramosh and Bugrote valleys in Gilgit, northern areas of Pakistan. Pak. J. Bot. 2008; 40(1):43-58.
Negi JS, Singh P, Joshi GP, Rawat MS, Bisht VK. Chemical constituents of Asparagus. Pharmacogn Rev. 2010; 4(8):215–20.
Singh SK, Singh S, Verma SK, Jain P, Dixit VK, Solanki S. A review on plants of genus polygonatum. Int J Res Dev Pharm L Sci. 2013; 2:387-97.
Wang K-J, Zhao J-L. Corn silk (Zea mays L.), a source of natural antioxidants with α-amylase, α-glucosidase, advanced glycation and diabetic nephropathy inhibitory activities. Biomed Pharmacother. 2019; 110:510-7.
Al-Yahya MA, Mossa JS, Ageel AM, Rafatullah S. Pharmacological and safety evaluation studies on Lepidium sativum L., Seeds. Phytomedicine. 1994; 1(2):155-9.
Ali H, Uddin S, Jalal S. Chemistry and Biological Activities of Berberis lycium Royle. J Biol Act Prod from Nat. 2015; 5(5):295-312.
Caceres A, Lopez BR, Giron MA, Logemann H. Plants used in guatemala for the treatment of dermatophytic infections. 1. Screening for antimycotic activity of 44 plant extracts. J Ethnopharmacol. 1991; 31(3):263-76.
Aadhan K, Anand S. Traditional remedial plants utilized in the Paliyar’s tribe handling of different skin diseases from Sadhuragiri hills, Tamil Nadu, india. J Drug Deliv Ther. 2019; 9(1):275-85.
Prescott TAK, Ariño J, Kite GC, Simmonds MSJ. Inhibition of human calcineurin and yeast calcineurin-dependent gene expression by Jasminum humile leaf and root extracts. J Ethnopharmacol. 2012 ; 140(2):293-7.
Jammu A, Shoaib Amjad M, Arshad M, Saboor A, Page S, Khalil Chaudhari S, et al. Ethnobotanical profiling of the medicinal flora of Kotli, Azad Jammu and Kashmir, Pakistan: Empirical reflections on multinomial logit specifications. Asian Pac J Trop Med. 2017; 10:503-14.
Bhatnagar M, Parwani L, Sharma V, Ganguli J. Hemostatic, antibacterial biopolymers from Acacia arabica (Lam.) Willd. and Moringa oleifera (Lam.) as potential wound dressing materials. Indian J. Exp. Biol. 2013; 51(10):804-810.
Shinwari MI, Khan MA. Folk use of medicinal herbs of Margalla Hills National Park, Islamabad. J Ethnopharmacol. 2000; 69(1):45-56.
Hosseini A, Hosseinzadeh H. A review on the effects of Allium sativum (Garlic) in metabolic syndrome. J Endocrinol Invest. 2015; 38(11):1147-57.
Al-Snafi AE. The constituents and biological effects of Arundo donax-A review. Int. J. Phytopharm.2015; 6(1):34-40.
Liji K, Arya V. Study on medicinal properties of common plants used in Ayurveda. Int. J. Botany Stud. 2018; 3(1):39-43.
Nain J, Saini V, Dhahiya S, Nain P. Evaluation of Anxiolytic Effects of Various Bark Extracts of Dalbergia Sissoo in Mice. J. Pharm. Res. 2011; 4(12):4485-7.
Grover JK, Yadav S, Vats V. Medicinal plants of India with anti-diabetic potential. J Ethnopharmacol. 2002; 81(1):81–100.
Murad W, Ahmad A, Gilani SA, Khan MA. Indigenous knowledge and folk use of medicinal plants by the tribal communities of Hazar Nao Forest, Malakand District, North Pakistan. J. Med. Plants Res.. 2011; 5(7):1072-86.
Sharma VA, Agrawal RC. Glycyrrhiza glabra-a plant for the future. Mintage J Pharm Med Sci. 2013; 2(3):15-20.
Das PR, Akter S, Islam MT, Kabir MH, Haque MM, Khatun Z, et al. A selection of medicinal plants used for treatment of diarrhea by folk medicinal practitioners of Bangladesh. Am Eurasian J Agric Environ Sci. 2012; 6(3):153-61.
Zaheer I, Rahman SZ, Khan RA, Parveen M, Ahmad M. Evaluation of Analgesic Activity of Extracts of Delphinium denudatum in Animal Models: A Dose Dependent Pre-Clinical Trial. J. clin. diagn. res. 2018; 12(12):01-04.
GANIE SA, ZARGAR BA, MASOOD A, ZARGAR MA. Hepatoprotective and Antioxidant Activity of Rhizome of Podophyllum hexandrum against Carbon Tetra Chloride Induced Hepatotoxicity in Rats. Biomed Environ Sci. 2013; 26(3):209–21.
Ahmad B, Naz S, Rauf A, Bashir S, Khan A, Farooq U, et al. In vivo study on analgesic, gastrointestinal tract (GIT) motility, and anti-termite potential of methanolic extract of Sarcococca saligna (D. Don) Muell. fruits. South African J Bot. 2018; 114:40-3.
Al-Khalil S. A Survey of Plants Used in Jordanian Traditional Medicine. Int J Pharmacogn. 1995; 33(4):317–23.
Ibrahim LF, Kawashty SA, Baiuomy AR, Shabana MM, El-Eraky WI, El-Negoumy SI. A comparative study of the flavonoids and some biological activities of two Chenopodium species. Chem Nat Compd. 2007; 43(1):24-8.
Kumar V, Singh P, Bhattacharya S. Anti-inflammatory and analgesic activity of Indian Hypericum perforatum L. Indian J. Exp. Biol. 2001; 39(4):339-343.
Rahmatullah M, Sultan S, Toma T, Lucky S, Chowdhury M, Haque W, et al. Effect of Cuscuta reflexa stem and Calotropis procera leaf extracts on glucose tolerance in glucose-induced hyperglycemic rats and mice. Afr. J. Tradit. Complement. Altern. Med.2010; 7(2):109-112.
Mustafa A, Ahmad A, Tantray AH, Parry PA. Ethnopharmacological Potential and Medicinal Uses of Miracle Herb Dioscorea spp. J. Ayu. Her. Med. 2018; 4(2):79-85.
Haq F, Ahmad H, Alam M. Traditional uses of medicinal plants of Nandiar Khuwarr catchment (District Battagram), Pakistan. J. Med. Plants Res. 2011; 5(1):39-48.
Rashid S, Ahmad M, Zafar M, Sultana S, Ayub M, Khan MA, et al. Ethnobotanical survey of medicinally important shrubs and trees of Himalayan region of Azad Jammu and Kashmir, Pakistan. J Ethnopharmacol. 2015 ; 166:340-51.
Krishnaveni A, Thaakur SR. Pharmacognostical and preliminary phytochemical studies of achyranthes aspera linn. Anc Sci Life. 2006; 26(1):1-5.
Oommachan M, Khan SS. Plants in aid of family planning programme. Anc Sci Life. 1981; 1(1):67-9.
Baliga MS, Baliga BRV, Kandathil SM, Bhat HP, Vayalil PK. A review of the chemistry and pharmacology of the date fruits (Phoenix dactylifera L.). Food Res Int. 2011; 44(7):1812-22.
Qasim M, Abideen Z, Adnan MY, Ansari R, Gul B, Khan MA. Traditional ethnobotanical uses of medicinal plants from coastal areas. J coast life Med. 2014; 2(1):22-30.
Aburjai T, Natsheh FM. Plants used in cosmetics. Phyther Res. 2003; 17(9):987-1000.
Kapoor R, Ali M, Mir SR, Raﬁullah MRM. Essential oil constituents of aerial parts ofArtemisia scoparia Waldst. & Kit. Flavour Fragr J. 2004; 19(2):109-11.
Ahmad M, Waheed I, Khalil-ur-Rehman M, Niaz U, Hassan SS. A review on Carthamus oxycantha. Pak J Pharm. 2007; 1:20-3.
Quratulain MA, Rafique MK, Ahmad MA, Mahmood R. Management of Macrosiphum rosae L. on different cultivars of Rosa indica L. by using different botanical extracts and detergent solution. Pak Entomol. 2015; 37:15-20.
Arun M, Asha VV. Gastroprotective effect of Dodonaea viscosa on various experimental ulcer models. J Ethnopharmacol. 2008; 118(3):460-5.
Ismail S, Nisar MF. Ethnomedicinal survey for important plants of district Lodhran, Punjab, Pakistan. BIOL (E-Journal of Life Sciences). 2010; 1(3):52-8.
Saddiqi HA, Iqbal Z. Usage and significance of fennel (foeniculum vulgare mill.) seeds in eastern medicine. Nuts and Seeds in Health and Disease Prevention, 1st Ed. Academic Press, Elsevier Inc.; 2011,461–7.
Babar M, Najam-us-Sahar SZ, Ashraf M, Kazi AG. Antiviral drug therapy-exploiting medicinal plants. J Antivir Antiretrovir. 2013; 5(02):028-36.
Hasan S. Pharmacological and medicinal uses of Achyranthes aspera. Int. J. Environ. Sci. Technol. 2014; 3(1):123-9.
Qasim M, Gulzar S, Khan MA. Halophytes as medicinal plants. Urbanisation, Land Use, Land Degradation and Environment. 1st Ed. New Delhi: Daya Publishing House; 2011, 330-343.
Adnan M, Bibi R, Azizullah A, Andaleeb R, Mussarat S, Tariq A, et al. Ethnomedicinal plants used against common digestive problems. African J Tradit Complement Altern Med. 2015; 12(5):99-117.
Javan R, Javadi B, Feyzabadi Z. Breastfeeding: A Review of Its Physiology and Galactogogue Plants in View of Traditional Persian Medicine. Breastfeed Med. 2017; 12(7):401-9.
Bahmani M, Rafieian-Kopaei M, Karamati SA, Bahmani F, Bahmani F, Bahmani E, et al. Antiparasitic herbs used in west regions of Ilam province located in west of Iran. Asian Pacific J Trop Dis. 2014; 4:S764-9.
Khan MI, Hanif W. Ethnoveterinary medicinal uses of plants from S am ali ni Valley Dist. Bhimber,(Azad Kashmir) Pakistan. Asian J Plant Sci. 2006; 5(2):390-6.
Hossain E, Chandra G, Nandy AP, Mandal SC, Gupta JK. Anthelmintic effect of a methanol extract of Bombax malabaricum leaves on Paramphistomum explanatum. Parasitol Res. 2012; 110(3):1097-102.
El-Ghazali GE, Al-Khalifa KS, Saleem GA, Abdallah EM. Traditional medicinal plants indigenous to Al-Rass province, Saudi Arabia. J Med Plants Res. 2010; 4(24):2680-3.
Ghori MK, Ghaffari MA, Hussain SN, Manzoor M, Aziz M, Sarwer W. Ethnopharmacological, phytochemical and pharmacognostic potential of genus Heliotropium L. Turk. J. Pharm. Sci. 2016; 13:143-68.
Akhtar S, Akhtar N, Kazim S, Khan T. Study of ethno-gynecologically important medicinal and other plants used for women specific purposes in Murtazaabad, Hunza, Pakistan. Nat Sci. 2016; 14:36-9.
Guo L-C, Zhao M-M, Sun W, Teng H-L, Huang B-S, Zhao X-P. Differentiation of the Chinese minority medicinal plant genus Berchemia spp. by evaluating three candidate barcodes. Springerplus. 2016; 5(1):658(1-10).
Sahu TR. An Ethnobotanical study of Madhya Pradesh 1: Plants used against various disorders among tribal women. Anc. Sci. Life 1982; 1(3):178-81.
Londonkar R. Potential Antibacterial and Antifungal Activity of Achyranthes aspera L. Recent res. sci. technol. 2011; 3(4):53-57.
Phondani PC, Bhatt A, Elsarrag E, Horr YA. Ethnobotanical magnitude towards sustainable utilization of wild foliage in Arabian Desert. J Tradit Complement Med. 2016; 6(3):209-18.
Kumar D, Prasad DN, Bhatnagar SP. Comparision of Diuretic activity of ethanolic extract of Aerva lanata (linn.) juss. ex. Schult & Aerva tomentosa forsk. Family: Amaranthaceae. Anc. Sci. Life 2005; 25(2):66-68.
Simin K, Khaliq-uz-Zaman SM, Ahmad VU. Antimicrobial activity of seed extracts and bondenolide fromCaesalpinia bonduc (L.) Roxb. Phyther Res. 2001; 15(5):437-40.
Babar MM, Kazi AG. Plant Pharmacogenomics: From Drug Discovery to Personalized Ethnomedicine. PlantOmics: The Omics of Plant Science, 1st Ed. New Dehli: Springer; 2015, 699-730.
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