Pathogenesis of COVID-19 associated with organ-based comorbidities

  • Faiza Naseer Senior lecturer, Department of Basic Medical Sciences, Shifa College of Pharmaceutical Sciences, Shifa Tameer-e-Millat University, Islamabad, Pakistan
  • Hafsa Bibi Student, Shifa College of Pharmaceutical Sciences, Shifa Tameer-e-Millat University, Islamabad, Pakistan
Keywords: Covid-19, organ comorbidities

Abstract

The rapid outbreak of Covid-19 which emerged from severe acute respiratory syndrome coronavirus 2 infection, has lately become a worldwide emergency. This has caused an enormous adverse impact globally. In this review article, studies related to pathogenesis of Covid-19 related comorbidities with different organs are viewed and summarized.

 

Downloads

Download data is not yet available.

References

Mohanty SK, Satapathy A, Naidu MM, et al. Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) and coronavirus disease 19 (COVID-19) - anatomic pathology perspective on current knowledge. Diagn Pathol. 2020; 15(1):103.

DOI: https://doi.org/10.1186/s13000-020-01017-8

Payne S. Family Coronaviridae. Viruses. 2017;149-158.

DOI: https://doi.org/10.1016/B978-0-12-803109-4.00017-9

Backer JA, Klinkenberg D, Wallinga J. Incubation period of 2019 novel coronavirus (2019-nCoV) infections among travellers from Wuhan, China, 20-28 January 2020. Euro Surveill. 2020; 25(5):2000062.

DOI: https://doi.org/10.2807/1560-7917.ES.2020.25.5.2000062

Jayaweera M, Perera H, Gunawardana B, Manatunge J. Transmission of COVID-19 virus by droplets and aerosols: A critical review on the unresolved dichotomy. Environ Res. 2020; 188:109819.

DOI: https://doi.org/10.1016/j.envres.2020.109819

Chiu NC, Chi H, Tai YL, Peng CC, Tseng CY, Chen CC. et al. Impact of Wearing Masks, Hand Hygiene, and Social Distancing on Influenza, Enterovirus, and All-Cause Pneumonia During the Coronavirus Pandemic: Retrospective National Epidemiological Surveillance Study. J Med Internet Res. 2020; 22(8):e21257.

DOI: https://doi.org/10.2196/21257

Yang X, Yu Y, Xu J, Shu H, Liu H, Wu Y. et al. Clinical features of patients with 2019 novel coronavirus in Wuhan, China. Lancet. 2020.

DOI: https://doi.org/10.1016/S0140-6736(20)30183-5

Chen N, Zhou M, Dong X, et al. Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study. Lancet. 2020.

DOI: https://doi.org/10.1016/S2213-2600(20)30079-5

Wang D, Hu B, Hu C, Zhu F, Liu X, Zhang J. et al. Clinical Characteristics of 138 Hospitalized Patients With 2019 Novel Coronavirus-Infected Pneumonia in Wuhan, China. JAMA. 2020. 323(11):1061-9.

DOI: https://doi.org/10.1001/jama.2020.1585

Liu K, Fang YY, Deng Y, Liu W, Wang MF, Ma JP. et al. Clinical characteristics of novel coronavirus cases in tertiary hospitals in Hubei Province. Chin Med J (Engl). 2020

DOI: https://doi.org/10.1097/CM9.0000000000000744

Xu XW, Wu XX, Jiang XG, Xu KJ, Ying LJ, Ma CL. et al. Clinical findings in a group of patients infected with the 2019 novel coronavirus (SARS-Cov-2) outside of Wuhan, China: retrospective case studies. BMJ. 2020.

DOI: https://doi.org/10.1136/bmj.m606

Chan JF, Yuan S, Kok KH, To KK, Chu H, Yang J, Xing F, Liu J, Yip CC, Poon RW, Tsoi HW. A familial cluster of pneumonia associated with the 2019 novel coronavirus indicating person-to-person transmission: a study of a family cluster. Lancet. 2020; 395(10223):514-23.

DOI: https://doi.org/10.1016/S0140-6736(20)30154-9

Zhang S, Li H, Huang S, You W, Sun H. High-resolution CT features of 17 cases of Corona Virus Disease 2019 in Sichuan province, China. Eur Respir J. 2020; 1(55)4.

DOI: https://doi.org/10.1183/13993003.00334-2020

Wang L, Gao YH, Iou L, Zhang GJ. The clinical dynamics of 18 cases of COVID-19 outside of Wuhan, China. Eur Respir J. 2020; 1(55)4.

DOI: https://doi.org/10.1183/13993003.00398-2020

Wang L, Gao YH, Iou L, Zhang GJ. et al. Epidemiological characteristics of 2019-ncoV infections in Shaanxi, China by February 8, 2020. Eur Respir J. 2020; 1(55)4.

DOI: https://doi.org/10.1183/13993003.00310-2020

Guan WJ, Ni ZY, Hu Y, Liang WH, Ou CQ, He JX. et al. Clinical Characteristics of Coronavirus Disease 2019 in China. N Engl J Med. 2020; 382(18):1708-20.

DOI: https://doi.org/10.1056/NEJMoa2002032

Guan WJ, Liang WH, Zhao Y, Liang HR, Chen ZS, Li YM. et al. Comorbidity and its impact on 1590 patients with COVID-19 in China: a nationwide analysis. Eur Respir J. 2020;55(5):2000547. Published 2020; 1(55)5.

DOI: https://doi.org/10.1183/13993003.00547-2020

Yang J, Zheng Y, Gou X, Pu K, Chen Z, Guo Q. et al. Prevalence of comorbidities and its effects in patients infected with SARS-CoV-2: a systematic review and meta-analysis. Int J Infect Dis. 2020; 94:91-95.

DOI: https://doi.org/10.1016/j.ijid.2020.03.017

Yang R, Gui X, Zhang Y, Xiong Y. The role of essential organ-based comorbidities in the prognosis of COVID-19 infection patients. Rev Respir Med. 2020;1-4.

DOI: https://doi.org/10.1080/17476348.2020.1761791

Richardson S, Hirsch JS, Narasimhan M, Crawford JM, McGinn T, Davidson KW. et al. Presenting Characteristics, Comorbidities, and Outcomes Among 5700 Patients Hospitalized With COVID-19 in the New York City Area. JAMA. 2020; 323(20):2052-2059.

DOI: https://doi.org/10.1001/jama.2020.6775

Singh AK, Gupta R, Ghosh A, Misra A, Diabetes in COVID-19: Prevalence, pathophysiology, prognosis and practical considerations, Diabetes & Metabolic Syndrome: Clin Res Review. 2020.

DOI: https://doi.org/10.1016/j.dsx.2020.04.004.

Chen T, Dai Z, Mo P, Li X, Ma Z, Song S, et al Chen X, Luo M, Liang K, Gao S, Zhang Y, Deng L, Xiong Y. Clinical Characteristics and Outcomes of Older Patients with Coronavirus Disease 2019 (COVID-19) in Wuhan, China: A Single-Centered, Retrospective Study. J Gerontol A Biol Sci Med Sci. 2020; 75(9):1788-1795.

DOI: https://doi.org/10.1093/gerona/glaa089.

Jutzeler CR, Bourguignon L, Weis CV, Tong B, Wong C, Rieck B, et. al. Comorbidities, clinical signs and symptoms, laboratory findings, imaging features, treatment strategies, and outcomes in adult and pediatric patients with COVID-19: A systematic review and meta-analysis. Travel Med Infect Dis. 2020; 37:101825.

DOI: https://doi.org/10.1016/j.tmaid.2020.101825.

Huang C, Wang Y, Li X, Ren L, Zhao J, Hu Y, et al. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. Lancet. 2020; 395(10223):497-506.

DOI: https://doi.org/10.1016/S0140-6736(20)30183-5

Holshue ML, DeBolt C, Lindquist S, Lofy KH, Wiesman J, Bruce H, et al. First case of 2019 novel coronavirus in the United States. N Engl J Med. 2020; 382:929-36.

DOI: https://doi.org/10.1056/NEJMoa2001191

Müller C, Karl N, Ziebuhr J, Pleschka S. D, L-Lysine acetylsalicylate+ glycine impairs coronavirus replication. J Antivir Antiretrovir. 2016; 8:142-50.

DOI: https://doi.org/10.4172/jaa.1000151

Fajgenbaum DC, Rader DJ. Teaching old drugs new tricks: statins for covID-19?. Cell Metabolism. 2020; 32(2):145-7.

DOI: https://doi.org/10.1016/j.cmet.2020.07.006

Published
2020-12-23
How to Cite
1.
Naseer F, Bibi H. Pathogenesis of COVID-19 associated with organ-based comorbidities. JSTMU [Internet]. 23Dec.2020 [cited 19Jun.2021];3(2):128-31. Available from: https://j.stmu.edu.pk/ojs/index.php/jstmu/article/view/90